EpiPen® Auto-Injectors

Handling instructions:

• The EpiPen® & EpiPen® Jr, contain 2mL epinephrine solution. Approximately 1.7 mL remains in the auto-injector after activation, but is not available for future use, and should be discarded.
• Selection of the appropriate dosage strength is determined according to patient body weight:
  • Patients 15 to 30 kg (33 pounds to 66 pounds): EpiPen® Jr 0.15 mg
  • Patients greater than or equal to 30 kg (approximately 66 pounds or more): EpiPen® 0.3 mg
• Inject EpiPen® or EpiPen® Jr intramuscularly or subcutaneously into the anterolateral aspect of the thigh, through clothing if necessary. Instruct caregivers of young children who are prescribed an EpiPen® and who may be uncooperative and kick or move during an injection to hold the leg firmly in place and limit movement prior to and during an injection.
• Protect from light. Epinephrine is light sensitive and should be stored in the carrier tube provided to protect it from light. Store at 20°C to 25°C; excursions permitted to 15°C to 30°C. Do not refrigerate.

Features and benefits:

• EpiPen (epinephrine injection, USP) is an auto-injector and combination product containing drug and device components.
• Used in the emergency treatment of allergic reactions including anaphylaxis, which may result from allergic reactions to insect stings or bites, foods, drugs, sera, diagnostic testing substances and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.
• The signs and symptoms associated with anaphylaxis include flushing, apprehension, syncope, tachycardia, unobtainable pulse associated with hypotension, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, airway swelling, laryngospasm, bronchospasm, pruritus, angioedema, swelling of the eyelids, lips, and tongue.

Availability

Epipen® Auto-Injectors are available in:

• EpiPen® Epi Inj Unidose 0.3 mg auto-injector (Adult), 1 Inj/Bx
• EpiPen® Jr Epi Inj Unidose 0.15 mg auto-inj (Jr), 1 Inj/Bx